BDBM50218723 7-amino-3-(4-amino-3-methoxy-phenyl)-5,10-dihydro-dibenzo[b,e][1,4]diazepin-11-one::CHEMBL243500

SMILES COc1cc(ccc1N)-c1ccc2c(Nc3cc(N)ccc3NC2=O)c1

InChI Key InChIKey=DWIPJLDMMUUBRZ-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50218723   

TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218723(7-amino-3-(4-amino-3-methoxy-phenyl)-5,10-dihydro-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant Chk1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218723(7-amino-3-(4-amino-3-methoxy-phenyl)-5,10-dihydro-...)
Affinity DataEC50:  4.99E+4nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50218723(7-amino-3-(4-amino-3-methoxy-phenyl)-5,10-dihydro-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Antiproliferative activity against HeLa cells by MTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed