BDBM50218677 CHEMBL242005::N-(5-tert-butyl-2-methoxy-3-(methylsulfonamido)phenyl)benzo[b]thiophene-2-carboxamide::benzo[b]thiophene-2-carboxylic acid (5-tert-Butyl-3-methanesulfonylamino-2-methoxy-phenyl)-amide

SMILES COc1c(NC(=O)c2cc3ccccc3s2)cc(cc1NS(C)(=O)=O)C(C)(C)C

InChI Key InChIKey=XEUYPMUQCOVVHK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218677   

TargetMitogen-activated protein kinase 14(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50218677(benzo[b]thiophene-2-carboxylic acid (5-tert-Butyl-...)
Affinity DataIC50: 2.70E+3nMAssay Description:Binding affinity to p38alpha assessed as inhibition of ATF2 phosphorylation preincubated for 4 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed