BDBM50218515 CHEMBL396199::benzyl-[4-(6,7-dimethoxy-2-oxo-2H-chromen-3-yl)benzyl]dimethylammoniumiodide

SMILES COc1cc2cc(-c3ccc(C[N+](C)(C)Cc4ccccc4)cc3)c(=O)oc2cc1OC

InChI Key InChIKey=OZPRPMGGGNQZCR-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50218515   

TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50218515(benzyl-[4-(6,7-dimethoxy-2-oxo-2H-chromen-3-yl)ben...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50218515(benzyl-[4-(6,7-dimethoxy-2-oxo-2H-chromen-3-yl)ben...)
Affinity DataIC50: 4.38E+4nMAssay Description:Inhibition of human recombinant BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50218515(benzyl-[4-(6,7-dimethoxy-2-oxo-2H-chromen-3-yl)ben...)
Affinity DataKi:  11nMAssay Description:Inhibition of recombinant human AChE assessed as hydrolysis of acetylthiocholine by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed