BDBM50218472 4-{5-ethyl-2-[2-(4-fluoro-phenyl)-acetylamino]-7,7,10,10-tetramethyl-7,8,9,10-tetrahydro-5H-5,13-diaza-benzo[4,5]cyclohepta[1,2-b]naphthalen-12-yl}-benzoic acid::CHEMBL237800

SMILES CCN1c2ccc(NC(=O)Cc3ccc(F)cc3)cc2N=C(c2ccc(cc2)C(O)=O)c2cc3c(cc12)C(C)(C)CCC3(C)C

InChI Key InChIKey=LYCNMFMZQGELCV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50218472   

TargetRetinoic acid receptor RXR-alpha(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50218472(4-{5-ethyl-2-[2-(4-fluoro-phenyl)-acetylamino]-7,7...)
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at human RXRalpha expressed in EK293 cells assessed as inhibition of LG-100268-induced transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50218472(4-{5-ethyl-2-[2-(4-fluoro-phenyl)-acetylamino]-7,7...)
Affinity DataIC50: 720nMAssay Description:Antagonist activity at human RXRalpha expressed in EK293 cells assessed as inhibition of 9-cis-retinoic acid-induced transactivationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed