BDBM50218246 CHEMBL68323

SMILES COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2cc(oc12)C(C)O

InChI Key InChIKey=VSLZRLVOASPJGZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50218246   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50218246(CHEMBL68323)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of Phosphodiesterase 4 from human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Rat)
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50218246(CHEMBL68323)
Affinity DataIC50: 19nMAssay Description:Inhibition of rolipram binding to rat brain tissue at 20 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2018
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50218246(CHEMBL68323)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of PDE4 in Homo sapiens (human) U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article