BDBM50218141 CHEMBL244190::N-tert-butyl-N'-[2-(3-iodophenoxy)-5-nitrobenzenesulfonyl]-urea

SMILES CC(C)(C)NC(=O)NS(=O)(=O)c1cc(ccc1Oc1cccc(I)c1)[N+]([O-])=O

InChI Key InChIKey=CDAXWGJBYYGYEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50218141   

TargetThromboxane A2 receptor(Human)
University of LièGe

Curated by ChEMBL
LigandPNGBDBM50218141(N-tert-butyl-N'-[2-(3-iodophenoxy)-5-nitrobenzenes...)
Affinity DataIC50: 95nMAssay Description:Antagonist activity at human thromboxane A2 receptor isoform beta expressed in HEK293 cells assessed as inhibition of U46619-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
University of LièGe

Curated by ChEMBL
LigandPNGBDBM50218141(N-tert-butyl-N'-[2-(3-iodophenoxy)-5-nitrobenzenes...)
Affinity DataIC50: 470nMAssay Description:Antagonist activity at human thromboxane A2 receptor isoform alpha expressed in HEK293 cells assessed as inhibition of U46619-induced calcium mobiliz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed