BDBM50218138 CHEMBL390216::N-tert-butyl-N'-[2-(2-chlorophenoxy)-5-nitrobenzenesulfonyl]-urea

SMILES CC(C)(C)NC(=O)NS(=O)(=O)c1cc(ccc1Oc1ccccc1Cl)[N+]([O-])=O

InChI Key InChIKey=RACMNPDRNUNRGY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50218138   

TargetThromboxane A2 receptor(Human)
University of LièGe

Curated by ChEMBL
LigandPNGBDBM50218138(N-tert-butyl-N'-[2-(2-chlorophenoxy)-5-nitrobenzen...)
Affinity DataIC50: 205nMAssay Description:Antagonist activity at human thromboxane A2 receptor isoform beta expressed in HEK293 cells assessed as inhibition of U46619-induced calcium mobiliza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
University of LièGe

Curated by ChEMBL
LigandPNGBDBM50218138(N-tert-butyl-N'-[2-(2-chlorophenoxy)-5-nitrobenzen...)
Affinity DataIC50: 2.42E+3nMAssay Description:Antagonist activity at human thromboxane A2 receptor isoform alpha expressed in HEK293 cells assessed as inhibition of U46619-induced calcium mobiliz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed