BDBM50218116 CHEMBL244403::naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone

SMILES CCCCCOc1ccc(C(=O)c2cccc3ccccc23)c2ccccc12

InChI Key InChIKey=RSUMDJRTAFBISX-UHFFFAOYSA-N

Data  4 KI  12 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50218116   

TargetCytochrome P450 2C19(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataIC50: 1.58E+3nMAssay Description:Displacement of [3H]SR141716A from membrane bound human CB1 receptor after 1 hr by beta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataIC50: 5.30E+3nMAssay Description:Displacement of [3H]CP55940 from membrane bound human CB2 receptor after 1 hr by beta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataEC50:  73nMAssay Description:Agonist activity at human CB1 receptor expressed in HEK293 cells assessed as [35S]GTPgamma bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataIC50: 98nMAssay Description:Displacement of [3H]CP-55940 human CB2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataIC50: 22nMAssay Description:Inhibition of rat CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataIC50: 8.08E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataEC50:  28nMAssay Description:Agonist activity at human CB2 receptor expressed in CHOK1 cells assessed as reversal of forskolin-evoked cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of CYP2C8 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCytochrome P450 2E1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of CYP2E1 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataEC50:  6.10nMAssay Description:Agonist activity at human CB1 receptor expressed in HEK293 cells assessed as reversal of forskolin-evoked cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataEC50:  72nMAssay Description:Agonist activity at human CB1 receptor expressed in HEK293 EBNA cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataKi:  19nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataKi:  19nMAssay Description:Binding affinity to human CB2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50218116(naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methan...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]-CP55,940 from human CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed