BDBM50217906 3-benzenesulfonyl-1-(1-methyl-pyrrolidin-3-yl)-1Hpyrrolo[2,3-b]pyridine::CHEMBL399013

SMILES CN1CCC(C1)n1cc(c2cccnc12)S(=O)(=O)c1ccccc1

InChI Key InChIKey=JHBBHOBPEAOEFU-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50217906   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217906(3-benzenesulfonyl-1-(1-methyl-pyrrolidin-3-yl)-1Hp...)
Affinity DataEC50:  2.04E+3nMAssay Description:Agonist activity at human 5HT6 expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217906(3-benzenesulfonyl-1-(1-methyl-pyrrolidin-3-yl)-1Hp...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217906(3-benzenesulfonyl-1-(1-methyl-pyrrolidin-3-yl)-1Hp...)
Affinity DataKi:  2.51nMAssay Description:Binding affinity to 5HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed