BDBM50217888 3-(phenylsulfonyl)sulfonyl]-1-piperidin-3-yl-1Hpyrrolo[2,3-b]pyridine::CHEMBL235070

SMILES O=S(=O)(c1cn(C2CCCNC2)c2ncccc12)c1ccccc1

InChI Key InChIKey=UEJRENXOUHNGKE-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50217888   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217888(3-(phenylsulfonyl)sulfonyl]-1-piperidin-3-yl-1Hpyr...)
Affinity DataEC50:  47nMAssay Description:Agonist activity at human 5HT6 expressed in HeLa cells assessed as intracellular cAMP level by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217888(3-(phenylsulfonyl)sulfonyl]-1-piperidin-3-yl-1Hpyr...)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]LSD from cloned human 5HT6 expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50217888(3-(phenylsulfonyl)sulfonyl]-1-piperidin-3-yl-1Hpyr...)
Affinity DataKi:  4.90nMAssay Description:Binding affinity to 5HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed