BDBM50217137 CHEMBL388710::Ethyl 2-(4-Methylphenyl)-2-oxoethyl Trithiocarbonate::trithiocarbonic acid ethyl ester 2-oxo-2-p-tolyl-ethyl ester

SMILES CCSC(=S)SCC(=O)c1ccc(C)cc1

InChI Key InChIKey=AEKWVQVKWFZHDI-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50217137   

TargetHistone deacetylase 1(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50217137(Ethyl 2-(4-Methylphenyl)-2-oxoethyl Trithiocarbona...)
Affinity DataIC50: 6.99E+3nMAssay Description:Inhibition of recombinant HDAC1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50217137(Ethyl 2-(4-Methylphenyl)-2-oxoethyl Trithiocarbona...)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of recombinant HDAC6 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50217137(Ethyl 2-(4-Methylphenyl)-2-oxoethyl Trithiocarbona...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of HDAC1 in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Nycomed

Curated by ChEMBL
LigandPNGBDBM50217137(Ethyl 2-(4-Methylphenyl)-2-oxoethyl Trithiocarbona...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of recombinant HDAC1 expressed in HEK293 cells using variable substrate concentration by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed