BDBM50216817 (3R)-6-cyclohexyl-N-hydroxy-3-(3-{[(phenylsulfonyl)amino]carbonyl}-1,2,4-oxadiazol-5-yl)hexanamide::CHEMBL439012

SMILES ONC(=O)C[C@@H](CCCC1CCCCC1)c1nc(no1)C(=O)NS(=O)(=O)c1ccccc1

InChI Key InChIKey=JBPHFUSOSQRLMX-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50216817   

TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216817((3R)-6-cyclohexyl-N-hydroxy-3-(3-{[(phenylsulfonyl...)
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216817((3R)-6-cyclohexyl-N-hydroxy-3-(3-{[(phenylsulfonyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216817((3R)-6-cyclohexyl-N-hydroxy-3-(3-{[(phenylsulfonyl...)
Affinity DataIC50: 9.20E+4nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216817((3R)-6-cyclohexyl-N-hydroxy-3-(3-{[(phenylsulfonyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216817((3R)-6-cyclohexyl-N-hydroxy-3-(3-{[(phenylsulfonyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216817((3R)-6-cyclohexyl-N-hydroxy-3-(3-{[(phenylsulfonyl...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human procollagen C-proteinase expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216817((3R)-6-cyclohexyl-N-hydroxy-3-(3-{[(phenylsulfonyl...)
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed