BDBM50216790 (3R)-6-cyclohexyl-3-[3-(2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-1,2,4-oxadiazol-5-yl]-N-hydroxyhexanamide::CHEMBL226852

SMILES ONC(=O)C[C@@H](CCCC1CCCCC1)c1nc(no1)-c1c[nH]c(=O)[nH]c1=O

InChI Key InChIKey=SWOIHXOGQYPPNC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50216790   

TargetMatrix metalloproteinase-14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216790((3R)-6-cyclohexyl-3-[3-(2,4-dioxo-1,2,3,4-tetrahyd...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216790((3R)-6-cyclohexyl-3-[3-(2,4-dioxo-1,2,3,4-tetrahyd...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216790((3R)-6-cyclohexyl-3-[3-(2,4-dioxo-1,2,3,4-tetrahyd...)
Affinity DataIC50: 7.96E+4nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBone morphogenetic protein 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216790((3R)-6-cyclohexyl-3-[3-(2,4-dioxo-1,2,3,4-tetrahyd...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human procollagen C-proteinase expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216790((3R)-6-cyclohexyl-3-[3-(2,4-dioxo-1,2,3,4-tetrahyd...)
Affinity DataIC50: 4.96E+4nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216790((3R)-6-cyclohexyl-3-[3-(2,4-dioxo-1,2,3,4-tetrahyd...)
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed