BDBM50216685 (4-chlorophenyl)(4-(8-nitroquinolin-5-yl)piperazin-1-yl)methanone::CHEMBL226115

SMILES [O-][N+](=O)c1ccc(N2CCN(CC2)C(=O)c2ccc(Cl)cc2)c2cccnc12

InChI Key InChIKey=KLNPVNZJCWIQSK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50216685   

TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50216685((4-chlorophenyl)(4-(8-nitroquinolin-5-yl)piperazin...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant SIRT3 using fluorescent peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50216685((4-chlorophenyl)(4-(8-nitroquinolin-5-yl)piperazin...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant SIRT2 using fluorescent peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50216685((4-chlorophenyl)(4-(8-nitroquinolin-5-yl)piperazin...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant SIRT1 using fluorescent peptide substrate by fluorescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50216685((4-chlorophenyl)(4-(8-nitroquinolin-5-yl)piperazin...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of sirtuin 2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed