BDBM50216453 CHEMBL247537::dimethyl-{4-[(E)-3-(4'-methyl-biphenyl-4-yl)-acryloylamino]-benzyl}-(tetrahydro-pyran-4-yl)-ammonium

SMILES Cc1ccc(cc1)-c1ccc(\C=C\C(=O)Nc2ccc(C[N+](C)(C)C3CCOCC3)cc2)cc1

InChI Key InChIKey=URKNLZLJINOYBX-UHFFFAOYSA-O

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216453   

TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50216453(dimethyl-{4-[(E)-3-(4'-methyl-biphenyl-4-yl)-acryl...)
Affinity DataIC50: 10nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed