BDBM50216421 1-(4-hydroxy-benzyl)-5-[2-(pyridin-3-yl-oxymethyl)-pyrrolidine-1-sulfonyl]-1H-indole-2,3-dione::CHEMBL227035

SMILES Oc1ccc(CN2C(=O)C(=O)c3cc(ccc23)S(=O)(=O)N2CCC[C@H]2COc2cccnc2)cc1

InChI Key InChIKey=OCRBUZYTFNEEGD-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50216421   

TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50216421(1-(4-hydroxy-benzyl)-5-[2-(pyridin-3-yl-oxymethyl)...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human recombinant caspase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-6(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50216421(1-(4-hydroxy-benzyl)-5-[2-(pyridin-3-yl-oxymethyl)...)
Affinity DataIC50: 9.55E+3nMAssay Description:Inhibition of human recombinant caspase 6More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-1(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50216421(1-(4-hydroxy-benzyl)-5-[2-(pyridin-3-yl-oxymethyl)...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant caspase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-8(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50216421(1-(4-hydroxy-benzyl)-5-[2-(pyridin-3-yl-oxymethyl)...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant caspase 8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-7(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50216421(1-(4-hydroxy-benzyl)-5-[2-(pyridin-3-yl-oxymethyl)...)
Affinity DataIC50: 11.7nMAssay Description:Inhibition of human recombinant caspase 7More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCaspase-3(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50216421(1-(4-hydroxy-benzyl)-5-[2-(pyridin-3-yl-oxymethyl)...)
Affinity DataIC50: 3.89nMAssay Description:Inhibition of caspase3More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed