BDBM50215894 3-(4-hydroxy-phenyl)-1-propyl-1,2,3,4-tetrahydro-quinolin-7-ol::CHEMBL391619

SMILES CCCN1CC(Cc2ccc(O)cc12)c1ccc(O)cc1

InChI Key InChIKey=ANWMFPKWFILNBY-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50215894   

TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215894(3-(4-hydroxy-phenyl)-1-propyl-1,2,3,4-tetrahydro-q...)
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215894(3-(4-hydroxy-phenyl)-1-propyl-1,2,3,4-tetrahydro-q...)
Affinity DataIC50: 2.47E+3nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215894(3-(4-hydroxy-phenyl)-1-propyl-1,2,3,4-tetrahydro-q...)
Affinity DataIC50: 2.65E+3nMAssay Description:Antagonist activity at ERalpha expressed in yeast AH109 assessed as inhibition of 17-beta-estradiol induced alpha-galactosidase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215894(3-(4-hydroxy-phenyl)-1-propyl-1,2,3,4-tetrahydro-q...)
Affinity DataEC50:  4.75E+3nMAssay Description:Agonist activity at human ERbeta expressed in yeast AH109 by yeast two hybrid assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed