BDBM50215891 3-(4-hydroxy-phenyl)-1-methyl-1,2,3,4-tetrahydro-quinolin-7-ol::CHEMBL239723

SMILES CN1CC(Cc2ccc(O)cc12)c1ccc(O)cc1

InChI Key InChIKey=LUFRGFLTIGIXEQ-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50215891   

TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215891(3-(4-hydroxy-phenyl)-1-methyl-1,2,3,4-tetrahydro-q...)
Affinity DataIC50: 220nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215891(3-(4-hydroxy-phenyl)-1-methyl-1,2,3,4-tetrahydro-q...)
Affinity DataIC50: 2.95E+3nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215891(3-(4-hydroxy-phenyl)-1-methyl-1,2,3,4-tetrahydro-q...)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human ERbeta expressed in yeast AH109 by yeast two hybrid assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215891(3-(4-hydroxy-phenyl)-1-methyl-1,2,3,4-tetrahydro-q...)
Affinity DataEC50:  1.52E+4nMAssay Description:Agonist activity at human ERalpha expressed in yeast AH109 by yeast two hybrid assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed