BDBM50215890 1-cyclopropylmethyl-3-(4-hydroxy-phenyl)-1,2,3,4-tetrahydro-quinolin-7-ol::CHEMBL392029

SMILES Oc1ccc(cc1)C1CN(CC2CC2)c2cc(O)ccc2C1

InChI Key InChIKey=PBOCTFMUGOZFAM-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50215890   

TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215890(1-cyclopropylmethyl-3-(4-hydroxy-phenyl)-1,2,3,4-t...)
Affinity DataEC50:  6.89E+3nMAssay Description:Agonist activity at human ERbeta expressed in yeast AH109 by yeast two hybrid assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215890(1-cyclopropylmethyl-3-(4-hydroxy-phenyl)-1,2,3,4-t...)
Affinity DataIC50: 1.63E+3nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215890(1-cyclopropylmethyl-3-(4-hydroxy-phenyl)-1,2,3,4-t...)
Affinity DataIC50: 230nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215890(1-cyclopropylmethyl-3-(4-hydroxy-phenyl)-1,2,3,4-t...)
Affinity DataIC50: 5.57E+3nMAssay Description:Antagonist activity at ERalpha expressed in yeast AH109 assessed as inhibition of 17-beta-estradiol induced alpha-galactosidase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed