BDBM50215855 CHEMBL51467

SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(F)cc(F)c1C(O)=O

InChI Key InChIKey=QHSZIPGOPZVWKD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50215855   

TargetLeukotriene B4 receptor 1/2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215855(CHEMBL51467)
Affinity DataIC50: 5nMAssay Description:Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1/2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215855(CHEMBL51467)
Affinity DataIC50: 200nMAssay Description:Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophils in whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1/2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215855(CHEMBL51467)
Affinity DataIC50: 40nMAssay Description:Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1/2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215855(CHEMBL51467)
Affinity DataIC50: 300nMAssay Description:Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed