BDBM50215740 CHEMBL48906

SMILES O[C@@H]1[C@@H](Cc2ccc(cc2)-c2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1C(O)=O

InChI Key InChIKey=ZCLRUNQNSPWNJW-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50215740   

TargetLeukotriene B4 receptor 1/2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215740(CHEMBL48906)
Affinity DataIC50: 56nMAssay Description:Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1/2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215740(CHEMBL48906)
Affinity DataIC50: 56nMAssay Description:Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1/2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215740(CHEMBL48906)
Affinity DataIC50: 280nMAssay Description:Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1/2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215740(CHEMBL48906)
Affinity DataIC50: 700nMAssay Description:Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophils in whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1/2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215740(CHEMBL48906)
Affinity DataIC50: 700nMAssay Description:Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophils in whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1/2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215740(CHEMBL48906)
Affinity DataIC50: 4nMAssay Description:Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1/2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215740(CHEMBL48906)
Affinity DataIC50: 4nMAssay Description:Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed
TargetLeukotriene B4 receptor 1/2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215740(CHEMBL48906)
Affinity DataIC50: 280nMAssay Description:Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2018
Entry Details Article
PubMed