BDBM50215507 6-methoxy-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid::CHEMBL245502

SMILES COc1ccc2[nH]c3C(CCCc3c2c1)C(O)=O

InChI Key InChIKey=LFQOVKSZZBTUJG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50215507   

TargetMAP kinase-activated protein kinase 2(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215507(6-methoxy-2,3,4,9-tetrahydro-1H-carbazole-1-carbox...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Guru Jambheshwar University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50215507(6-methoxy-2,3,4,9-tetrahydro-1H-carbazole-1-carbox...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of recombinant SIRT1 (unknown origin) assessed as deacetylation activity using acetylated p53 as substrate measured after 2 hrs by Fluor d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2018
Entry Details Article
PubMed