BDBM50215444 5-METHYL-7-(2-METHYLPROPYL)-2-(NAPHTHALEN-1-YLMETHYL)-3-PYRIDIN-4-YL-2H-PYRAZOLO[3,4-D]PYRIMIDINE-4,6(5H,7H)-DIONE::7-isobutyl-5-methyl-2-(1-naphthylmethyl)-3-pyridin-4-yl-2H-pyrazolo[3,4-d]pyrimidine-4,6-(5H,7H)-dione::7-isobutyl-5-methyl-2-(naphthalen-1-ylmethyl)-3-(pyridin-4-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione::CHEMBL401874

SMILES CC(C)CN1c2c(c(n(n2)Cc3cccc4c3cccc4)c5ccncc5)C(=O)N(C1=O)C

InChI Key InChIKey=NNZDBCPMOOEFTE-UHFFFAOYSA-N

Data  4 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50215444   

TargetGlutamate racemase(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215444BDBM50215444(7-isobutyl-5-methyl-2-(naphthalen-1-ylmethyl)-3-(p...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Helicobacter pylori MurIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate racemase(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215444BDBM50215444(7-isobutyl-5-methyl-2-(naphthalen-1-ylmethyl)-3-(p...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Helicobacter pylori glutamate racemaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate racemase(Helicobacter pylori (strain J99 / ATCC 700824) (Ca...)
Mazandaran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215444BDBM50215444(7-isobutyl-5-methyl-2-(naphthalen-1-ylmethyl)-3-(p...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Helicobacter pylori Glutamate racemaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlutamate racemase(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215444BDBM50215444(7-isobutyl-5-methyl-2-(naphthalen-1-ylmethyl)-3-(p...)
Affinity DataKd:  2.90E+3nMAssay Description:Binding affinity to Helicobacter pylori MurI by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate racemase(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215444BDBM50215444(7-isobutyl-5-methyl-2-(naphthalen-1-ylmethyl)-3-(p...)
Affinity DataKd:  3.90E+3nMAssay Description:Binding affinity to Helicobacter pylori MurI by protein fluorescence binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate racemase(Helicobacter pylori (strain J99 / ATCC 700824) (Ca...)
Mazandaran University of Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215444BDBM50215444(7-isobutyl-5-methyl-2-(naphthalen-1-ylmethyl)-3-(p...)
Affinity DataIC50: 5.90E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMedPDB3D3D Structure (crystal)
TargetGlutamate racemase(Streptococcus pneumoniae D39)
Astrazeneca Global Structural Chemistry

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50215444BDBM50215444(7-isobutyl-5-methyl-2-(naphthalen-1-ylmethyl)-3-(p...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of MurI in Streptococcus pneumoniaeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed