BDBM50215241 CHEMBL297813

SMILES CC(=O)c1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(sc2c1)-c1ccc(O)cc1

InChI Key InChIKey=MHZGNGBSYZVXAY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50215241   

TargetEstrogen receptor beta(Human)TBA
LigandPNGBDBM50215241(CHEMBL297813)
Affinity DataIC50: 60nMAssay Description:Antagonist effect in breast tissue was assayed by inhibition of estrogen stimulated MCF-7 cell proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2018
Entry Details

TargetEstrogen receptor beta(Human)TBA
LigandPNGBDBM50215241(CHEMBL297813)
Affinity DataIC50: 60nMAssay Description:Antagonism of estrogen action in a mammary tumor cell line was assayed via inhibition of MCF-7 cell proliferation stimulated by 10 e-11 M 17-beta-est...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed