BDBM50214545 (S)-4-methylsulfanyl-2-{(S)-4-methyl-2-[(S)-2,2,2-trifluoro-1-(4'-methanesulfonyl-biphenyl-4-yl)-ethylamino]-pentanoylamino}-butyric acid methyl ester::CHEMBL427712

SMILES COC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)N[C@@H](c1ccc(cc1)-c1ccc(cc1)S(C)(=O)=O)C(F)(F)F

InChI Key InChIKey=WWEDKOLRRSGJDB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50214545   

TargetCathepsin K(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50214545((S)-4-methylsulfanyl-2-{(S)-4-methyl-2-[(S)-2,2,2-...)
Affinity DataIC50: 27nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed