BDBM50214441 CHEMBL389687::octanedioic acid [2'-(2-amino-3-phenylpropionylamino)-biphenyl-4-yl]amide hydroxyamide

SMILES N[C@@H](Cc1ccccc1)C(=O)Nc1ccccc1-c1ccc(NC(=O)CCCCCCC(=O)NO)cc1

InChI Key InChIKey=SZYFHRXJYNBDKS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50214441   

TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214441(octanedioic acid [2'-(2-amino-3-phenylpropionylami...)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of His-tagged HDAC6 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214441(octanedioic acid [2'-(2-amino-3-phenylpropionylami...)
Affinity DataIC50: 46.1nMAssay Description:Inhibition of His-tagged HDAC10 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214441(octanedioic acid [2'-(2-amino-3-phenylpropionylami...)
Affinity DataIC50: 156nMAssay Description:Inhibition of His-tagged HDAC2 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214441(octanedioic acid [2'-(2-amino-3-phenylpropionylami...)
Affinity DataIC50: 40.9nMAssay Description:Inhibition of His-tagged HDAC1 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214441(octanedioic acid [2'-(2-amino-3-phenylpropionylami...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of His-tagged HDAC8 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase(Human)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50214441(octanedioic acid [2'-(2-amino-3-phenylpropionylami...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human HDAC in HeLa cells by fluorescent activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed