BDBM50214439 CHEMBL227170::octanedioic acid {2'-[2-amino-3-(4-hydroxy-phenyl)propionylamino]biphenyl-4-yl}amide hydroxyamide

SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)Nc1ccccc1-c1ccc(NC(=O)CCCCCCC(=O)NO)cc1

InChI Key InChIKey=BKQJCMOVBFAIQR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50214439   

TargetHistone deacetylase 8(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214439(octanedioic acid {2'-[2-amino-3-(4-hydroxy-phenyl)...)
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of His-tagged HDAC8 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214439(octanedioic acid {2'-[2-amino-3-(4-hydroxy-phenyl)...)
Affinity DataIC50: 36.9nMAssay Description:Inhibition of His-tagged HDAC1 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214439(octanedioic acid {2'-[2-amino-3-(4-hydroxy-phenyl)...)
Affinity DataIC50: 42.1nMAssay Description:Inhibition of His-tagged HDAC10 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214439(octanedioic acid {2'-[2-amino-3-(4-hydroxy-phenyl)...)
Affinity DataIC50: 205nMAssay Description:Inhibition of His-tagged HDAC2 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214439(octanedioic acid {2'-[2-amino-3-(4-hydroxy-phenyl)...)
Affinity DataIC50: 9nMAssay Description:Inhibition of His-tagged HDAC6 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed