BDBM50214437 6-(3-adamantan-1-yl-ureido)hexanoic acid hydroxyamide::CHEMBL227118

SMILES ONC(=O)CCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2

InChI Key

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50214437   

TargetHistone deacetylase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214437(6-(3-adamantan-1-yl-ureido)hexanoic acid hydroxyam...)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of His-tagged HDAC2 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214437(6-(3-adamantan-1-yl-ureido)hexanoic acid hydroxyam...)
Affinity DataIC50: 173nMAssay Description:Inhibition of His-tagged HDAC10 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214437(6-(3-adamantan-1-yl-ureido)hexanoic acid hydroxyam...)
Affinity DataIC50: 102nMAssay Description:Inhibition of His-tagged HDAC6 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214437(6-(3-adamantan-1-yl-ureido)hexanoic acid hydroxyam...)
Affinity DataIC50: 152nMAssay Description:Inhibition of His-tagged HDAC1 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214437(6-(3-adamantan-1-yl-ureido)hexanoic acid hydroxyam...)
Affinity DataIC50: 3.41E+3nMAssay Description:Inhibition of His-tagged HDAC8 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214437(6-(3-adamantan-1-yl-ureido)hexanoic acid hydroxyam...)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed