BDBM50214431 8-[3-(4-dimethylaminobenzyl)ureido]octanoic acid hydroxyamide::CHEMBL227119

SMILES CN(C)c1ccc(CNC(=O)NCCC(=O)NO)cc1

InChI Key InChIKey=FJIZCQBWUCHHAR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50214431   

TargetPolyamine deacetylase HDAC10(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214431(8-[3-(4-dimethylaminobenzyl)ureido]octanoic acid h...)
Affinity DataIC50: 178nMAssay Description:Inhibition of His-tagged HDAC10 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214431(8-[3-(4-dimethylaminobenzyl)ureido]octanoic acid h...)
Affinity DataIC50: 130nMAssay Description:Inhibition of His-tagged HDAC1 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214431(8-[3-(4-dimethylaminobenzyl)ureido]octanoic acid h...)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of His-tagged HDAC8 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214431(8-[3-(4-dimethylaminobenzyl)ureido]octanoic acid h...)
Affinity DataIC50: 492nMAssay Description:Inhibition of His-tagged HDAC2 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50214431(8-[3-(4-dimethylaminobenzyl)ureido]octanoic acid h...)
Affinity DataIC50: 45.5nMAssay Description:Inhibition of His-tagged HDAC6 expressed in Sf9 cells by fluorescence-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed