BDBM50214251 (5R,8R,11S)-5-[(3-chlorophenyl)methyl]-11-[(dimethylamino)methyl]-8-(propan-2-yl)-3,4,5,6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-2H-1,4,7,10,13-benzoxatetrazacyclooctadecine-6,9,12-trione::CHEMBL400635

SMILES CC(C)[C@H]1NC(=O)[C@@H](Cc2cccc(Cl)c2)NCCOc2ccccc2CCCNC(=O)[C@H](CN(C)C)NC1=O

InChI Key InChIKey=SISNPNGRBBSGJD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50214251   

TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214251((5R,8R,11S)-5-[(3-chlorophenyl)methyl]-11-[(dimeth...)
Affinity DataIC50: 95nMAssay Description:Antagonist activity against human motilin receptor in aequoscreen cells assessed as inhibition of motilin induced calcium release by aequorin assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214251((5R,8R,11S)-5-[(3-chlorophenyl)methyl]-11-[(dimeth...)
Affinity DataKi:  27nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed