BDBM50214207 (2S)-2-{4-butoxy-3-[({[2-fluoro-4-(trifluoromethyl)phenyl]carbonyl}amino)methyl]benzyl}butanoic acid::(S)-2-(4-butoxy-3-((2-fluoro-4-(trifluoromethyl)benzamido)methyl)benzyl)butanoic acid::CHEMBL375471

SMILES CCCCOc1ccc(C[C@H](CC)C(O)=O)cc1CNC(=O)c1ccc(cc1F)C(F)(F)F

InChI Key InChIKey=AJSFKATVCYWKJN-UHFFFAOYSA-N

Data  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50214207   

TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50214207((S)-2-(4-butoxy-3-((2-fluoro-4-(trifluoromethyl)be...)
Affinity DataEC50:  250nMAssay Description:Effect on PPARalpha transactivation activity in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50214207((S)-2-(4-butoxy-3-((2-fluoro-4-(trifluoromethyl)be...)
Affinity DataEC50:  0.910nMAssay Description:Effect on PPARdelta transactivation activity in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50214207((S)-2-(4-butoxy-3-((2-fluoro-4-(trifluoromethyl)be...)
Affinity DataEC50:  1.10E+3nMAssay Description:Effect on PPARgamma transactivation activity in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50214207((S)-2-(4-butoxy-3-((2-fluoro-4-(trifluoromethyl)be...)
Affinity DataEC50:  0.720nMAssay Description:Agonist activity at PPARdelta receptor expressed in HEK293 cells co-transfected with GAL4 by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50214207((S)-2-(4-butoxy-3-((2-fluoro-4-(trifluoromethyl)be...)
Affinity DataEC50:  240nMAssay Description:Agonist activity at PPARalpha receptor expressed in HEK293 cells co-transfected with GAL4 by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50214207((S)-2-(4-butoxy-3-((2-fluoro-4-(trifluoromethyl)be...)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at PPARgamma receptor expressed in HEK293 cells co-transfected with GAL4 by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50214207((S)-2-(4-butoxy-3-((2-fluoro-4-(trifluoromethyl)be...)
Affinity DataEC50:  250nMAssay Description:Transactivation of Gal4-fused human PPARalpha expressed in HEK293 cells after 16 to 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50214207((S)-2-(4-butoxy-3-((2-fluoro-4-(trifluoromethyl)be...)
Affinity DataEC50:  0.720nMAssay Description:Transactivation of Gal4-fused human PPARdelta expressed in HEK293 cells after 16 to 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2013
Entry Details Article
PubMed