BDBM50213944 CHEMBL399096::isobutyl 3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-3-(hydroxycarbamoyl)piperidine-1-carboxylate

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)C(=O)OCC(C)C)C(=O)NO

InChI Key InChIKey=AGMWQNDXCWDRDZ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50213944   

TargetMatrix metalloproteinase-14(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50213944(isobutyl 3-((4-(but-2-ynyloxy)phenylsulfonyl)methy...)
Affinity DataIC50: 3.41E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50213944(isobutyl 3-((4-(but-2-ynyloxy)phenylsulfonyl)methy...)
Affinity DataIC50: 3.41E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50213944(isobutyl 3-((4-(but-2-ynyloxy)phenylsulfonyl)methy...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50213944(isobutyl 3-((4-(but-2-ynyloxy)phenylsulfonyl)methy...)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50213944(isobutyl 3-((4-(but-2-ynyloxy)phenylsulfonyl)methy...)
Affinity DataIC50: 960nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50213944(isobutyl 3-((4-(but-2-ynyloxy)phenylsulfonyl)methy...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50213944(isobutyl 3-((4-(but-2-ynyloxy)phenylsulfonyl)methy...)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50213944(isobutyl 3-((4-(but-2-ynyloxy)phenylsulfonyl)methy...)
Affinity DataIC50: 960nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed