BDBM50213934 CHEMBL398325::tylophorinine

SMILES COc1ccc2c3[C@@H](O)[C@@H]4CCCN4Cc3c3cc(OC)c(OC)cc3c2c1

InChI Key InChIKey=LAWAARLALKUFQQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50213934   

TargetTranscription factor Jun(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50213934(tylophorinine | CHEMBL398325)
Affinity DataIC50: 110nMAssay Description:Inhibition of AP1-mediated gene transcription in HepG2 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed