BDBM50213745 7-chloro-1,1-dioxo-3-(2-trifluoromethyl-phenylamino)-1,4-dihydro-1lambda6-benzo[1,2,4]thiadiazin-5-ol::CHEMBL397068

SMILES Oc1cc(Cl)cc2c1N=C(Nc1ccccc1C(F)(F)F)NS2(=O)=O

InChI Key InChIKey=OQOVFBCDOYXCAA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50213745   

TargetC-X-C chemokine receptor type 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50213745(7-chloro-1,1-dioxo-3-(2-trifluoromethyl-phenylamin...)
Affinity DataIC50: 830nMAssay Description:Antagonist activity at CXCR2 receptor expressed in CHOK1 cells assessed as human IL8-induced calcium mobilization by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed