BDBM50213536 CHEMBL538397::N-((1s,4s)-4-(4-(2-(2-fluoroethoxy)phenyl)piperidin-1-yl)cyclohexyl)-3,4-dimethoxybenzenesulfonamide

SMILES COc1ccc(cc1OC)S(=O)(=O)N[C@H]1CC[C@H](CC1)N1CCC(CC1)c1ccccc1OCCF

InChI Key InChIKey=NZOIFXLLVJGITJ-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50213536   

TargetAlpha-1D adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50213536(N-((1s,4s)-4-(4-(2-(2-fluoroethoxy)phenyl)piperidi...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity to human cloned adrenergic alpha-1d receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50213536(N-((1s,4s)-4-(4-(2-(2-fluoroethoxy)phenyl)piperidi...)
Affinity DataKi:  8.5nMAssay Description:Binding affinity to human cloned adrenergic alpha-1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50213536(N-((1s,4s)-4-(4-(2-(2-fluoroethoxy)phenyl)piperidi...)
Affinity DataKi:  8.80nMAssay Description:Binding affinity to human cloned adrenergic alpha-1d receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50213536(N-((1s,4s)-4-(4-(2-(2-fluoroethoxy)phenyl)piperidi...)
Affinity DataKi:  11nMAssay Description:Binding affinity to human cloned adrenergic Alpha-1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50213536(N-((1s,4s)-4-(4-(2-(2-fluoroethoxy)phenyl)piperidi...)
Affinity DataKi:  201nMAssay Description:Binding affinity for dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50213536(N-((1s,4s)-4-(4-(2-(2-fluoroethoxy)phenyl)piperidi...)
Affinity DataKi:  330nMAssay Description:Binding affinity to human cloned dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50213536(N-((1s,4s)-4-(4-(2-(2-fluoroethoxy)phenyl)piperidi...)
Affinity DataKi:  354nMAssay Description:Binding affinity to human cloned adrenergic alpha-1b receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50213536(N-((1s,4s)-4-(4-(2-(2-fluoroethoxy)phenyl)piperidi...)
Affinity DataKi:  401nMAssay Description:Binding affinity to human cloned adrenergic alpha-1b receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed