BDBM50213304 (Z)-5-(4-Hydroxy-3-methoxybenzylidene)thiazolidine-2,4-dione::5-(4-hydroxy-3-methoxybenzylidene)-2,4-thiazolidinedione::CHEMBL232380

SMILES COc1cc(\C=C2/SC(=O)NC2=O)ccc1O

InChI Key InChIKey=KAICHBSRWFIESE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50213304   

TargetAldo-keto reductase family 1 member B1 [K65Q](Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50213304(5-(4-hydroxy-3-methoxybenzylidene)-2,4-thiazolidin...)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of bovine aldose reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Alma Mater Studiorum-University of Bologna

Curated by ChEMBL
LigandPNGBDBM50213304(5-(4-hydroxy-3-methoxybenzylidene)-2,4-thiazolidin...)
Affinity DataIC50: 6.01E+3nMAssay Description:Inhibition of GSK3beta (unknown origin) using GS-2 peptide substrate incubated for 30 mins by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed