BDBM50212926 (1S,2R,5S)-5-(isoindolin-2-yl)-2-(2,4,5-trifluorophenyl)cyclohexanamine::CHEMBL392924

SMILES N[C@H]1C[C@H](CC[C@@H]1c1cc(F)c(F)cc1F)N1Cc2ccccc2C1

InChI Key InChIKey=HODJCMYQBLFCSM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50212926   

TargetProlyl endopeptidase FAP(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212926((1S,2R,5S)-5-(isoindolin-2-yl)-2-(2,4,5-trifluorop...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of FAPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212926((1S,2R,5S)-5-(isoindolin-2-yl)-2-(2,4,5-trifluorop...)
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212926((1S,2R,5S)-5-(isoindolin-2-yl)-2-(2,4,5-trifluorop...)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212926((1S,2R,5S)-5-(isoindolin-2-yl)-2-(2,4,5-trifluorop...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212926((1S,2R,5S)-5-(isoindolin-2-yl)-2-(2,4,5-trifluorop...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed