BDBM50212789 1-(5-amino-5-oxopentyl)-N-cyclohexyl-N-methyl-2-(thiophene-2-carboxamido)-1H-benzo[d]imidazole-5-carboxamide::CHEMBL232769

SMILES CN(C1CCCCC1)C(=O)c1ccc2n(CCCCC(N)=O)c(NC(=O)c3cccs3)nc2c1

InChI Key InChIKey=XUYIOELVCRUWKB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212789   

TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212789(1-(5-amino-5-oxopentyl)-N-cyclohexyl-N-methyl-2-(t...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212789(1-(5-amino-5-oxopentyl)-N-cyclohexyl-N-methyl-2-(t...)
Affinity DataIC50: 3.10E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed