BDBM50212748 3-(4-hydroxybenzylidene)-5,6-dimethoxyindolin-2-one::CHEMBL391567

SMILES COc1cc2NC(=O)\C(=C\c3ccc(O)cc3)c2cc1OC

InChI Key InChIKey=JGSMCYNBVCGIHC-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50212748   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
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Curated by ChEMBL

LigandBDBM50212748(3-(4-hydroxybenzylidene)-5,6-dimethoxyindolin-2-on...)Copy SMILESCopy InChI

Affinity DataIC50: 170nMAssay Description:Inhibition of RET in mouse NIH3T3MEN2A cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
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