BDBM50212680 2-(3-chloro-4-(trifluoromethoxy)phenyl)-5-(3,5-dichlorophenyl)-4,5-dihydro-1H-imidazole::CHEMBL247113

SMILES FC(F)(F)Oc1ccc(cc1Cl)C1=NC(CN1)c1cc(Cl)cc(Cl)c1

InChI Key InChIKey=PCSHOZRRLWJMKY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212680   

TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212680(2-(3-chloro-4-(trifluoromethoxy)phenyl)-5-(3,5-dic...)
Affinity DataIC50: 3.67E+3nMAssay Description:Antagonist activity at NMDA NR2B receptor assessed as calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212680(2-(3-chloro-4-(trifluoromethoxy)phenyl)-5-(3,5-dic...)
Affinity DataKi:  223nMAssay Description:Binding affinity to NMDA NR2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed