BDBM50212617 CHEMBL374818::Dmt-Pro-Emp-Phe-NH2

SMILES CCc1cccc(C)c1C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key InChIKey=FZEQHIVEBCRYJC-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50212617   

TargetMu-type opioid receptor(Guinea pig)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50212617(Dmt-Pro-Emp-Phe-NH2 | CHEMBL374818)
Affinity DataIC50: 0.170nMAssay Description:Agonist activity at mu opioid receptor in Hartley guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50212617(Dmt-Pro-Emp-Phe-NH2 | CHEMBL374818)
Affinity DataIC50: 0.510nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50212617(Dmt-Pro-Emp-Phe-NH2 | CHEMBL374818)
Affinity DataKi:  0.210nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosome membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50212617(Dmt-Pro-Emp-Phe-NH2 | CHEMBL374818)
Affinity DataKi:  3.03nMAssay Description:Displacement of [3H]deltorphin 2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosome membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50212617(Dmt-Pro-Emp-Phe-NH2 | CHEMBL374818)
Affinity DataKi:  278nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor in Hartley guinea pig cerebellum P2 synaptosome membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed