BDBM50212611 CHEMBL413892::Tyr-Pro-3,5Dmp-Phe-NH2

SMILES Cc1cc(C)cc(C[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)c1

InChI Key InChIKey=WGUOAUNVYIRMQJ-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50212611   

TargetDelta-type opioid receptor(Mouse)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50212611(Tyr-Pro-3,5Dmp-Phe-NH2 | CHEMBL413892)
Affinity DataIC50: 1.00E+4nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50212611(Tyr-Pro-3,5Dmp-Phe-NH2 | CHEMBL413892)
Affinity DataIC50: 389nMAssay Description:Agonist activity at mu opioid receptor in Hartley guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50212611(Tyr-Pro-3,5Dmp-Phe-NH2 | CHEMBL413892)
Affinity DataKi:  6.19nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosome membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Kobe Gakuin University

Curated by ChEMBL
LigandPNGBDBM50212611(Tyr-Pro-3,5Dmp-Phe-NH2 | CHEMBL413892)
Affinity DataKi:  3.45E+3nMAssay Description:Displacement of [3H]deltorphin 2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosome membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed