BDBM50212384 CHEMBL557356::threo-1-aza-4beta-hydroxy-5-phenyl[4.4.0]decane hydrochloride

SMILES O[C@H]1CCN2CCCC[C@@H]2[C@H]1c1ccccc1

InChI Key InChIKey=VYNNWWZBPKXCNX-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50212384   

TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50212384(threo-1-aza-4beta-hydroxy-5-phenyl[4.4.0]decane hy...)
Affinity DataIC50: 680nMAssay Description:Inhibition of [3H]DA uptake at DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50212384(threo-1-aza-4beta-hydroxy-5-phenyl[4.4.0]decane hy...)
Affinity DataKi:  108nMAssay Description:Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50212384(threo-1-aza-4beta-hydroxy-5-phenyl[4.4.0]decane hy...)
Affinity DataKi:  351nMAssay Description:Displacement of [3H]nisoxetine from NET in Sprague-Dawley rat cortical tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed