BDBM50212382 CHEMBL537652::threo-1-aza-4alpha-hydroxy-5-(3,4-dichlorophenyl)[4.4.0]decane hydrochloride

SMILES O[C@@H]1CCN2CCCC[C@@H]2[C@H]1c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=SLAPDCZJLWVMFZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50212382   

TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50212382(threo-1-aza-4alpha-hydroxy-5-(3,4-dichlorophenyl)[...)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50212382(threo-1-aza-4alpha-hydroxy-5-(3,4-dichlorophenyl)[...)
Affinity DataKi:  367nMAssay Description:Displacement of [3H]nisoxetine from NET in Sprague-Dawley rat cortical tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50212382(threo-1-aza-4alpha-hydroxy-5-(3,4-dichlorophenyl)[...)
Affinity DataKi:  2.05E+3nMAssay Description:Displacement of [3H]citalopram from 5HTT in Sprague-Dawley rat cerebrumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed