BDBM50212376 (1R,9aR)-1-phenyl-hexahydro-1H-quinolizin-4(6H)-one hydrocloride::CHEMBL541898

SMILES O=C1CC[C@@H]([C@H]2CCCCN12)c1ccccc1

InChI Key InChIKey=JXMPKLBLDBKBJN-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50212376   

TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50212376((1R,9aR)-1-phenyl-hexahydro-1H-quinolizin-4(6H)-on...)
Affinity DataIC50: 8.49E+3nMAssay Description:Inhibition of [3H]DA uptake at DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50212376((1R,9aR)-1-phenyl-hexahydro-1H-quinolizin-4(6H)-on...)
Affinity DataKi:  3.55E+3nMAssay Description:Displacement of [3H]citalopram from 5HTT in Sprague-Dawley rat cerebrumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50212376((1R,9aR)-1-phenyl-hexahydro-1H-quinolizin-4(6H)-on...)
Affinity DataKi:  6.61E+3nMAssay Description:Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed