BDBM50212368 CHEMBL537429::threo-1-aza-5-(2-chlorophenyl)[4.4.0]decane hydrochloride

SMILES Clc1ccccc1[C@H]1CCCN2CCCC[C@H]12

InChI Key InChIKey=MIPMYILNWMGUSB-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50212368   

TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50212368(threo-1-aza-5-(2-chlorophenyl)[4.4.0]decane hydroc...)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of [3H]DA uptake at DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50212368(threo-1-aza-5-(2-chlorophenyl)[4.4.0]decane hydroc...)
Affinity DataKi:  480nMAssay Description:Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50212368(threo-1-aza-5-(2-chlorophenyl)[4.4.0]decane hydroc...)
Affinity DataKi:  1.84E+3nMAssay Description:Displacement of [3H]citalopram from 5HTT in Sprague-Dawley rat cerebrumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50212368(threo-1-aza-5-(2-chlorophenyl)[4.4.0]decane hydroc...)
Affinity DataKi:  2.75E+3nMAssay Description:Displacement of [3H]nisoxetine from NET in Sprague-Dawley rat cortical tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed