BDBM50212365 CHEMBL556365::threo-1-aza-5-(3,4-dichlorophenyl)[4.4.0]decane hydrochloride

SMILES Clc1ccc(cc1Cl)[C@H]1CCCN2CCCC[C@H]12

InChI Key InChIKey=ULFGSFGZNPXTPY-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50212365   

TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50212365(threo-1-aza-5-(3,4-dichlorophenyl)[4.4.0]decane hy...)
Affinity DataIC50: 11nMAssay Description:Inhibition of [3H]DA uptake at DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50212365(threo-1-aza-5-(3,4-dichlorophenyl)[4.4.0]decane hy...)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50212365(threo-1-aza-5-(3,4-dichlorophenyl)[4.4.0]decane hy...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]nisoxetine from NET in Sprague-Dawley rat cortical tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50212365(threo-1-aza-5-(3,4-dichlorophenyl)[4.4.0]decane hy...)
Affinity DataKi:  121nMAssay Description:Displacement of [3H]citalopram from 5HTT in Sprague-Dawley rat cerebrumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed