BDBM50212363 CHEMBL559186::erythro-1-aza-5-(3,4-dichlorophenyl)[4.4.0]decane hydrochloride

SMILES Clc1ccc(cc1Cl)[C@@H]1CCCN2CCCC[C@H]12

InChI Key InChIKey=ULFGSFGZNPXTPY-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50212363   

TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50212363(erythro-1-aza-5-(3,4-dichlorophenyl)[4.4.0]decane ...)
Affinity DataIC50: 88nMAssay Description:Inhibition of [3H]DA uptake at DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50212363(erythro-1-aza-5-(3,4-dichlorophenyl)[4.4.0]decane ...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]WIN-35428 from DAT in Sprague-Dawley rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50212363(erythro-1-aza-5-(3,4-dichlorophenyl)[4.4.0]decane ...)
Affinity DataKi:  102nMAssay Description:Displacement of [3H]citalopram from 5HTT in Sprague-Dawley rat cerebrumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50212363(erythro-1-aza-5-(3,4-dichlorophenyl)[4.4.0]decane ...)
Affinity DataKi:  160nMAssay Description:Displacement of [3H]nisoxetine from NET in Sprague-Dawley rat cortical tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed