BDBM50212282 CHEMBL3981026

SMILES Cc1cc(F)c(cc1-n1cnc(c1)C1CC1)C(=O)Nc1ccccn1

InChI Key InChIKey=CCQFNUGZTSLAOK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50212282   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50212282(CHEMBL3981026)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ASK1 catalytic domain (654 to 971 residues) expressed in baculovirus infected sf21 cells using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2018
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50212282(CHEMBL3981026)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of ASK1 (unknown origin) using biotin-MBP as substrate after 20 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2019
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50212282(CHEMBL3981026)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of ASK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed