BDBM50212146 1-ethyl-N-{[3-fluoro-5-(trifluoromethyl)phenyl]methyl}-3-[(1S,5'R)-5'-methylspiro[indene-1,4'-piperidine]-1'-yl]cyclopentane-1-carboxamide::CHEMBL230932

SMILES CCC1(CCC(C1)N1CC[C@]2(C=Cc3ccccc23)[C@@H](C)C1)C(=O)NCc1cc(F)cc(c1)C(F)(F)F

InChI Key InChIKey=WZPMKCZRNPIWHY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212146   

TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212146(1-ethyl-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50: 3.30nMAssay Description:Displacement of [125I]MCP1 from human CCR2 I40L mutant expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212146(1-ethyl-N-{[3-fluoro-5-(trifluoromethyl)phenyl]met...)
Affinity DataIC50: 3.5nMAssay Description:Displacement of [125I]MCP1 from mouse CCR2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed